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      This issue of Neuro Image wants to be a special tribute to Theodore Rasmussen who passed away last January. Dr William Feindel has prepared the insert, abstracted from the special memorial presentation at the Neuro on March 22nd. I personally have always enjoyed working with Ted Rasmussen, reviewing pneumograms and angiograms prior to his surgical treatment of epilepsy, or as participant of the Epilepsy Conference. He has always impressed me as a man of duty, expertise and honesty. Last September, he sent this short note upon reception of the Neuro Image issue on Charlie Hodge. The answer to his question: Vol. 1 No. 1 of NeuroImage was in 1984.

The neural circuit of Papez
Drs Maurizio Cogoni & Donatella Tampieri

Recent studies in patients with limbic epilepsy have identified abnormalities in the fornix and mamillary bodies in addition to the classical findings of hippocampal atrophy and gliosis.

In a preliminary review of 125 patients with temporal lobe epilepsy and unilateral hippocampal atrophy, we found ipsilateral fornix atrophy in 66 (52.8%) and atrophy of ipsilateral mammillary body in 38 (30.4%). This relatively high incidence of fornix atrophy could be a useful complementary imaging finding in temporal lobe epilepsy.

Studies have also pointed out that the abnormalities along the cicuit of Papez may represent an additional marker for evaluation of the seizure focus in bilateral mesial temporal sclerosis/atrophy.
More investigation of these structural changes is underway.

 

Left hippocampal atrophy:
fornix atrophy ()
mamillary body atrophy ()

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